The smart Trick of ceesdekker.net That Nobody is Discussing
The smart Trick of ceesdekker.net That Nobody is Discussing
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2009, discovery of a brand new phenotype for microbes in slender nanofluidic slits; and first detection of local protein structures along DNA using strong-state nanopores
Our group studies bacterial mobile division which is aiming to constitute a ‘bottom up biology’ in artificial cells that could autonomously divide. Our principal interest lies in mobile division, chromatin framework, and spatial Handle.
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I am able to barely think about how I, like a geneticist, would be capable of find out fundamental physics, not to mention contend at the very best. How did you go about this?
This yielded a breakthrough. Inside of only some months, we have been able to evaluate transportation by means of somebody solitary-walled carbon nanotube. Based on very low-temperature experiments by an excellent PhD university student in my group, Sander Tans (now a valued colleague and professor at Delft College of Technologies by having an active investigation lab at AMOLF in Amsterdam), we confirmed that carbon nanotubes have been legitimate quantum wires with really very long (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic behaviour.
Experimental section diagram of negatively supercoiled DNA measured by magnetic tweezers and fluorescence,
Due to the fact 2000 he moved to solitary-molecule biophysics and nanobiology, with study from DNA supercoiling studies of nucleosomes and DNA maintenance proteins to DNA translocation by nanopores. Just lately his analysis has centered on researching cell division with bacteria on chip, though his best curiosity is within the way of noticing synthetic cells.
He also identified time to jot down a number of textbooks, send Practically forty thousand tweets and guide An effective investigate group at Delft University of Technological know-how. ‘It doesn’t truly feel like get the job done’, he states. ‘I’m just terribly curious.’
‘You should not just think about the thoughts of tomorrow, and also take into account the queries of the working day soon after tomorrow’
Resolving the action dimensions in condensin-pushed DNA loop extrusion identifies ATP binding as being the action-making course of action
Since 2000 he moved to one-molecule biophysics and nanobiology, with analysis from studies of DNA loop extrusion and supercoiling to DNA translocation by nanopores. A lot more recently his exploration has focused on finding out chromatin structure and mobile division with germs on chip, though he is additionally seeking to eventually build synthetic cells from The underside up.
Nanoscientist Cees Dekker is an amiable and flamboyant man who seems Substantially youthful as opposed to 62 years he basically is – stylish glasses, psychedelic shirt, engaging smile – although not one particular to waste time. He requires his time, but not more than important.
Enable’s first appear back in the meanwhile any time you made a decision to change your aim from superconductivity and nanotubes to biology at the conclusion of the nineteen nineties.
The biophysicist from Delft – who has long cees dekker been One of the more cited experts while in the Netherlands For a long time – will take his duty to contribute into the clarification and popularisation of his operate on the border of physics and biology very seriously and consistently seems within the media; Otherwise to look at his operate, then about the relationship concerning science and his Christian faith.